Genalex download

GenAlEx 6 was originally developed as a teaching tool to facilitate teaching population genetic analysis at the graduate level Peakall and Smouse, GenAlEx operates within Microsoft Excel—the widely used spreadsheet software that forms part of the cross-platform Microsoft Office suite.

Packaging genetic analysis within a familiar and flexible environment resulted in quick understanding and effective performance of population genetic analyses. Taking advantage of the rich graphical options available within Excel, GenAlEx offers a wide range of graphical outputs that aid genetic data analysis and interpretation.

GenAlEx is now widely used by university teachers at both undergraduate and graduate levels around the world. Moreover, the software has also attracted a large number of researchers who utilize its unique features. Here we provide an update on the new features offered in GenAlEx 6. GenAlEx offers population genetic analysis of diploid codominant, haploid, haplotypic and binary genetic data from animals, plants and microorganisms.

It accommodates a wide range of genetic markers, including microsatellites SSRs , single-nucleotide polymorphisms SNPs , amplified fragment length polymorphisms and DNA sequences. Both allele frequency-based and distance-based analysis options are provided. Readers are referred to Peakall and Smouse for a more comprehensive outline of these standard procedures, data formats and data import options. GenAlEx 6.

Thus, the maximum numbers of loci and samples are vastly expanded and only constrained by memory. More than 30 different Excel graphs summarize the outcomes of genetic analyses. Graphics can be further manipulated with Excel options and easily converted to pdf or other publication-quality formats. There has been much recent debate about the utility of F ST as a measure of population genetic structure Jost, ; Ryman and Leimar, ; Whitlock, The calculation of these statistics was validated by comparison with the software GenoDive v2.

Shannon information indices have been widely used in ecology but largely overlooked in genetics despite offering a framework for quantifying biological diversity across multiple scales genes to landscapes.

GenAlEx offers the calculation of a series of Shannon indices, including the mutual information index S H UA , an alternative estimator of population structure.

The methods follow Sherwin et al. More than pages of documentation are provided. This includes Appendix 1 that outlines the statistical analyses used and their supporting references. The revised guide to GenAlEx 6. When combined with its user-friendly interface, rich graphical outputs for data exploration and publication, tools for data manipulation and export options to many other software packages, we believe that GenAlEx offers an ideal launching pad for population genetic analysis by students, teachers and researchers alike.

We thank the many students, teachers and researchers who have enthusiastically adopted GenAlEx as one of their tools, especially those who have offered suggestions for improvement.

Michaela Blyton revised the guide, performed extensive beta-testing and offered crucial advice on improving the user interface. Sasha Peakall re-designed the GenAlEx logo. Google Scholar. Google Preview. Oxford University Press is a department of the University of Oxford. It furthers the University's objective of excellence in research, scholarship, and education by publishing worldwide.

Sign In or Create an Account. Sign In. Advanced Search. Search Menu. Article Navigation. Close mobile search navigation Article Navigation. Volume Article Contents Abstract. Population genetic software for teaching and research—an update. Oxford Academic. Peter E. Associate Editor: Jonathan Wren.

Revision received:. This release for Excel running in Windows offered new access to all GenAlEx options via the Excel Ribbon, while at the same time remaining backwards compatible to Excel The location of the GenAlEx menu has depended on the version of Excel used, and the operating system. The Excel Ribbon now provides a common interface and access point to GenAlEx options across Excel versions and operating systems.

These minor, mostly cosmetic issues, have yet to be fully resolved. We apologize to our long-standing GenAlEx users on the Macintosh for these issues which are beyond our control. In this beta release of GenAlEx 6. Disclaimer: This program is provided free of charge by the authors. While every effort has been taken to ensure the accuracy of the results and the smooth operation of the program, we regret that we are unable to take responsibility for unintentional errors or problems that may be encountered by users.

We are also unable to provide individualized support for users of the program. If you are a new user, please refer to the extensive documentation we provide including the Guide to GenAlEx and the supporting tutorials, both of which offer step-by-step instructions.

On Mac it is compatible with Excel and Nonetheless, our recent tests in March show that most GenAlEx options do run successfully, but with some minor Dialog box and Ribbon button image issues.